"For the Sisterhood, there's a special satisfaction that comes with helping a friend in need, especially when it's someone as dear as Charlotte Hansen. Myra Rutledge's childhood friend has spent tens of thousands of dollars on remedies to boost longevity. But far from improving her health, the medications seem to be destroying it. Myra becomes suspicious of the trio of doctors in charge of the program, especially once the Sisterhood's investigations...

Members of the Sisterhood are contacted by Judge Pearl Barnes, who has assisted fourteen pregnant teenagers escape from a secret polygamist sect and needs the sisters' help to keep them hidden in a secure place.